SALL4 (6E3); 1ml; Predilute

Code: 385M-17 D2-231

General description

SALL4 is a zinc finger transcription factor. Anti-SALL4 demonstrates 100% sensitivity and stains more than 90% tumor cells in all intratubular germ cell n...


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€187.60 EACH
€230.75 inc. VAT

General description

SALL4 is a zinc finger transcription factor. Anti-SALL4 demonstrates 100% sensitivity and stains more than 90% tumor cells in all intratubular germ cell neoplasia, seminomas/dysgerminomas, embryonal carcinomas, and yolk sac tumor (YST) (both pediatric and postpubertal). Anti-SALL4 also stains most cases of teratoma and the mononucleated trophoblastic cells in choriocarcinomas. In contrast, non-germ cell tumors show no anti-SALL4 staining. Most non-testicular tumors from various organs and sites are negative for anti-SALL4, though an occasional carcinoma or sarcoma may show weak anti-SALL4 staining in less than 25% of tumor cells. In normal testicular tissue, positive, weak anti-SALL4 staining is observed in spermatogonia. In addition, a few (﹤5%) primary spermatocytes showed dot-like weak anti-SALL4 staining. Secondary spermatocytes, spermatids, spermatozoa, and Sertoli cells are negative for anti-SALL4. Leydig cells, rete testis, epididymis, spermatic cord fibroblasts, blood vessels, and hematopoietic cells are negative for anti-SALL4.

Legal Information

Cell Marque is a trademark of Sigma-Aldrich Co. LLC

Linkage

SALL4 Positive Control Slides, Product No. 385S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Other Notes

For Technical Service please contact: 800-665-7284 or email: [email protected]

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and ﹤0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Quality

IVDIVDIVDRUO

antibody formculture supernatant
antibody product typeprimary antibodies
biological sourcemouse
clone6E3, monoclonal
conjugateunconjugated
controldysgerminoma, seminoma
descriptionFor In Vitro Diagnostic Use in Select Regions (See Chart)
formbuffered aqueous solution
Gene Informationhuman ... SALL4(57167)
isotypeIgG1
manufacturer/tradenameCell Marque
packagingvial of 0.5 mL concentrate (385M-15), vial of 0.1 mL concentrate (385M-14), bottle of 1.0 mL predilute (385M-17), bottle of 7.0 mL predilute (385M-18), vial of 1.0 mL concentrate (385M-16)
Quality Level100, 500
shipped inwet ice
species reactivityhuman
storage temp.2-8°C
technique(s)immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
visualizationnuclear
This product has met the following criteria to qualify for the following awards:



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